Congratulations Dr. Doyle!

Our wonderful Shelby Doyle became the second graduate student in the lab from the Department of Biological Engineering at MIT to successfully defend her thesis, just in time for the well-earned holiday break in December of 2019!

Dr. Doyle’s thesis, entitled Modulating Oncogenic Transcription with Small Molecules, was a tour de force and emphasized various strategies to tackle AR-driven transcriptional programs. Keep an eye out for upcoming publications related to her thesis work around a selective CDK9 inhibitor and a chemical probe of the OXPHOS pathway! The lab is so proud of your accomplishments!

Shelby and Family relaxing after a job well done!

Congratulations Dr. Chen!!

Congratulations in the utmost to Dr. Andrew Chen, who successfully defended his thesis this week!!

Dr. Chen was the first graduate student to join the Koehler lab at the Koch Institute at MIT and is the first to meet the full requirements for the PhD in Biological Engineering at MIT from our group. His thesis, entitled Discovery and Characterization of a Small Molecule that Modulates c-Myc Mediated Transcription via Max Homodimer Stabilization, detailed his work in the development of our newly published chemical probe, KI-MS2-008, and the exciting work he pioneered to understand the impact of this molecule on MYC/MAX networks and transcriptional regulation.

Congratulations on a job well done!!