Koehler Lab
  • Team
  • Publications
  • Overview Small molecule microarray screening Small molecule probes of oncogenic transcription factors Structurally and mechanistically novel probes of deacetylase enzymes
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Koehler Lab

  • Team/
  • Publications/
  • Research/
    • Overview
    • Small molecule microarray screening
    • Small molecule probes of oncogenic transcription factors
    • Structurally and mechanistically novel probes of deacetylase enzymes
  • Probes/
  • Resources/
  • News/
  • Contact/
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Koehler Lab

News

Koehler Lab

  • Team/
  • Publications/
  • Research/
    • Overview
    • Small molecule microarray screening
    • Small molecule probes of oncogenic transcription factors
    • Structurally and mechanistically novel probes of deacetylase enzymes
  • Probes/
  • Resources/
  • News/
  • Contact/
October 28, 2022

Honored to be a part of this group

October 28, 2022/ Angela Koehler

https://news.mit.edu/2022/tenured-engineers-1024

October 28, 2022/ Angela Koehler/

Angela Koehler

  • My research life, in a nutshell
  • Catherine Henry is named as a 2023 ...
  • Team/
  • Publications/
  • Research/
    • Overview
    • Small molecule microarray screening
    • Small molecule probes of oncogenic transcription factors
    • Structurally and mechanistically novel probes of deacetylase enzymes
  • Probes/
  • Resources/
  • News/
  • Contact/

Koehler Lab

The Koehler Lab aims to innovate in the earliest stages of drug discovery by building chemical tools or technologies to assist in the process of target validation and by expanding the repertoire of protein targets that are considered to be druggable. We focus primarily on building chemical tools and methods for studying temporal aspects of transcriptional regulation in development and disease with a focus on cancer.

Koehler Lab News

  • October 2024
    • Oct 30, 2024 Collaborative Next Generation Chemistry Center is Launched with Berkeley, Duke, and The Broad Institute
    • Oct 30, 2024 Ashley Booth presents at Cancer Research Day Symposium
  • September 2024
    • Sep 23, 2024 Happy 30th to Cell Chemical Biology!
    • Sep 23, 2024 Visit from TAKII Seed
  • July 2024
    • Jul 1, 2024 Yichen Xiang named a 2024-2025 Takeda Fellow!
    • Jul 1, 2024 Hello to The Engine Accelerator
    • Jul 1, 2024 Farewell to Toshi!
    • Jul 1, 2024 Congratulations to Dr. Mo Toure!
  • December 2023
    • Dec 15, 2023 Bocheng is a 2023-2024 Convergence Scholar!
  • August 2023
    • Aug 28, 2023 Yichen Xiang awarded a Ludwig Center fellowship!
  • March 2023
    • Mar 29, 2023 This is cancer research at MIT
  • December 2022
    • Dec 2, 2022 Royalty joins the Koehler Lab to watch the Boston Celtics beat the Miami Heat
  • November 2022
    • Nov 17, 2022 Andrea Casiraghi named a 2023 Convergence Scholar!
    • Nov 8, 2022 Ben Leu starts to deliver drugs in the Anderson Lab
    • Nov 8, 2022 Congratulations to Dr. Catherine Henry
  • October 2022
    • Oct 28, 2022 My research life, in a nutshell
    • Oct 28, 2022 Honored to be a part of this group
  • September 2022
    • Sep 23, 2022 Catherine Henry is named as a 2023 Siebel Scholar!
    • Sep 4, 2022 It's not a good-bye but a see you later for Huarui
  • July 2022
    • Jul 25, 2022 New manuscript in Science - drug delivery, screening, cell biology, and machine learning combined to understand how different cancer cells respond to various nanoparticle formulations
  • June 2022
    • Jun 13, 2022 Congratulations to Leyna Duong!
    • Jun 13, 2022 Congratulations to Dr. Rob Wilson!
  • December 2021
    • Dec 22, 2021 Congrats to Morgan on her new Koch Institute Ludwig Center Postdoctoral Fellowship!
  • November 2021
    • Nov 17, 2021 Congrats to Maddy on being named a 2021-2022 Convergence Scholar
  • September 2021
    • Sep 13, 2021 The Trio visits MIT ahead of the first day of school
    • Sep 13, 2021 Welcome Morgan, Bonnie, Ben and Huarui!
    • Sep 13, 2021 New perspective piece in Nature Reviews Drug Discovery!
    • Sep 13, 2021 Congratulations to Mo Toure on his RISE Award!
  • December 2020
    • Dec 23, 2020 Goodbye and good luck!
  • November 2020
    • Nov 12, 2020 New paper out in Cell Chemical Biology!
    • Nov 5, 2020 Congratulations, Mo and Jasmin!
    • Nov 4, 2020 New paper out in ACS Chemical Biology!
    • Nov 2, 2020 Welcome, Maddy!
  • February 2020
    • Feb 7, 2020 Welcome to all of our new faces!
  • January 2020
    • Jan 22, 2020 Congratulations Dr. Doyle!
    • Jan 22, 2020 Taking a Moonshot at a rare pediatric cancer
    • Jan 22, 2020 Yulong Su named a Convergence Scholar!
  • November 2019
    • Nov 23, 2019 Congratulations Rob!
  • May 2019
    • May 1, 2019 Congratulations Dr. Chen!!
  • March 2019
    • Mar 14, 2019 New paper on our Max-directed chemical probe is out in Cell Chemical Biology!
    • Mar 1, 2019 Welcome Yulong, Julie, and Florian!
  • November 2018
    • Nov 26, 2018 Congratulations Shelby!
    • Nov 21, 2018 Congratulations to Brice!
    • Nov 8, 2018 Koehler Lab featured in MIT's Spectrum
  • September 2018
    • Sep 28, 2018 Kronos Bio opens shop at Lab Central!
    • Sep 25, 2018 Koehler Lab at AACR Annual Meeting 2018
    • Sep 17, 2018 Congratulations to Nick, Rob and Shelby!
    • Sep 14, 2018 New Look--And New Faces!
  • August 2018
    • Aug 7, 2018 Welcome Nick and Dave!
    • Aug 7, 2018 Welcome Rob; Congrats Andrew!
    • Aug 7, 2018 Group wins Deshpande grant for translation efforts
    • Aug 7, 2018 Welcome Helen, Thijs, and baby Arabella!
    • Aug 7, 2018 Koehler Lab Booth for the Cambridge Science Festival
    • Aug 7, 2018 Welcome Shelby!
    • Aug 7, 2018 Welcome Qiaoyi, Chuan-Xu, and Becky!
    • Aug 7, 2018 Welcome Megan, Rob! Congrats to Marius!
    • Aug 7, 2018 Move complete! Welcome Eric!
    • Aug 7, 2018 Welcome Andrew, Rohit, and the Vegas twins!

The Koehler Lab is supported through the generosity of our public and private funding partners.
We will gladly accommodate requests for greater accessibility of public content.