New paper out in ACS Chemical Biology!

We are excited to share that our collaborative effort to discover chemical probes for the cytokine IL-4 is now available for download at ACS Chemical Biology!

This work led by our collaborators in the laboratory of Dr. Arturo Vegas at Boston University was championed in our lab throughout the project’s lifetime by Becky Leifer. The newly published story describes the discovery and validation of the first known small molecule inhibitor of IL-4.

We extend congratulations to all involved!

Sean P. Quinnell, Becky S. Leifer, Stephen T. Nestor, Kelly Tan, Daniel F. Sheehy, Luke Ceo, Shelby K. Doyle, Angela N. Koehler, and Arturo J. Vegas. “A Small-Molecule Inhibitor to the Cytokine Interleukin-4.” ACS Chemical Biology 2020 15 (10), 2649-2654