Our collaborative work with the Hammond Lab and the Broad Institute around NanoPRISM was recently published in Science and covered in MIT News:
https://news.mit.edu/2022/how-different-cancer-cells-respond-drug-delivering-nanoparticles-0721
The Koehler Lab aims to innovate in the earliest stages of drug discovery by building chemical tools or technologies to assist in the process of target validation and by expanding the repertoire of protein targets that are considered to be druggable. We focus primarily on building chemical tools and methods for studying temporal aspects of transcriptional regulation in development and disease with a focus on cancer.
The Koehler Lab is supported through the generosity of our public and private funding partners.
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