Koehler Lab
  • Team
  • Publications
  • Overview Small molecule microarray screening Small molecule probes of oncogenic transcription factors Structurally and mechanistically novel probes of deacetylase enzymes
  • Probes
  • Resources
  • News
  • Contact

Koehler Lab

  • Team/
  • Publications/
  • Research/
    • Overview
    • Small molecule microarray screening
    • Small molecule probes of oncogenic transcription factors
    • Structurally and mechanistically novel probes of deacetylase enzymes
  • Probes/
  • Resources/
  • News/
  • Contact/
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Koehler Lab

External Links

Koehler Lab

  • Team/
  • Publications/
  • Research/
    • Overview
    • Small molecule microarray screening
    • Small molecule probes of oncogenic transcription factors
    • Structurally and mechanistically novel probes of deacetylase enzymes
  • Probes/
  • Resources/
  • News/
  • Contact/
 

Institutions and Affiliations

Koch High-Throughput Screening Facility

MIT Center for Precision Cancer Medicine

MIT Department of Biological Engineering

Broad Institute of MIT & Harvard

Chemistry in Cancer Research (CICR) Working Group, American Association for Cancer Research (AACR)

Kronos Bio

Media Content

"Tackling the Undruggable" presentation by Dr. Koehler, Broad Institute's Midsummer Nights' Science Series 2009

"Taming a Master Regulator" presentation by Dr. Koehler, Convergence Conference 2016

"Secret Life of Scientists" Interview with Dr. Koehler

 
 
  • Team/
  • Publications/
  • Research/
    • Overview
    • Small molecule microarray screening
    • Small molecule probes of oncogenic transcription factors
    • Structurally and mechanistically novel probes of deacetylase enzymes
  • Probes/
  • Resources/
  • News/
  • Contact/

Koehler Lab

The Koehler Lab aims to innovate in the earliest stages of drug discovery by building chemical tools or technologies to assist in the process of target validation and by expanding the repertoire of protein targets that are considered to be druggable. We focus primarily on building chemical tools and methods for studying temporal aspects of transcriptional regulation in development and disease with a focus on cancer.

Koehler Lab News

The Koehler Lab is supported through the generosity of our public and private funding partners.
We will gladly accommodate requests for greater accessibility of public content.