KIARv03.png

IUPAC: (1R,3R)-N1-(5-propylpyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine

MW: 259.36

cLogP: 1.04

SMILES: CCCC1=NC2=CC=NN2C(=C1)N[C@@H]3CC[C@H](C3)N

CAS: N/A

IC50: 150 nM (CDK9/cyclinT1 at 45 μM ATP), 7.6 µM (AR-V driven reporter), 7.7 µM (LNCaP viability), 7.9 µM (VCaP viability)

Citation: Cell Chemical Biology. October 20, 2020. https://doi.org/10.1016/j.chembiol.2020.10.001

Commercial Sources: Chembridge #94082098